BioMarin is almost every analyst's favorite takeover candidate. Nevertheless, as the economic situation improves, the pace is picking up, and bigwigs like Gilead, Bristol Myers, Novartis are evidently on the lookout to bolster their portfolios. Written by Scott Matusow. On the one hand, CAPLYTAs sales are growing significantly, on the other hand, the company has several product candidates with the potential to generate billions of dollars in sales in a few years. This developer of rare disease drug Soliris has been in acquisition crosshairs since 2016 - with Roche, Pfizer, Novartis and Amgen been reported as potential buyers. Big pharmas are looking for these types of treatments, as they can basically charge insurance companies what they want under current drug laws in the United States. Want the latest recommendations from Zacks Investment Research? It remains to be seen if the takeover rumors are just wishful thinking or will turn into reality. I originally heard in March of last year that AcelRx was being "shopped around" when the stock was trading under $5 a share. 10 stocks we like better than Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, it can pay to listen. Vertex and Regeneron would be the most likely to acquire their CRISPR-focused biotech. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. CRISPR Therapeutics CRSP is one of the leading gene-editing companies. Total consideration can reflect both cash and equity offered upfront in exchange for the acquired companys shares, but deals in which the upfront payment was not specified, or was less than $50 million, were not included. In the business of drug development, deals can be just as important as scientific breakthroughs. Sold Sepracor to Dainippon Sumitomo: Mr. Adams served as President and Chief Executive Officer of Sepracor Inc. Dainippon Sumitomo bought out Sepracor for $2.6B, or a 48% premium over the current share price. M&A deal flow dwindled in 2021, reflecting stricter antitrust laws. Bayer announced the acquisition of the global strategic imaging AI platform and solutions provider Blackford Analysis Ltd. Takeover rumors initially swirled around Clovis Oncology in 2013 when Rubraca, was in clinical trial stage. And there are often rumors of other deals that never materialize. 9. Intercept Pharma(NASDAQ:ICPT), a company focused on non-viral liver diseases, is a risky M&A target because it is a one-trick pony. Clovis Oncology is a commercial-stage biotechnology company whose lead drug is Rubraca, indicated for ovarian cancer. All rights reserved. When the symbol you want to add appears, add it to My Quotes by selecting it and pressing Enter/Return. Analyst Robert Hazlett said the Food and Drug Administration's recent decision to allow Acadia to file for marketing approval of its drug pimavanserin based on just one late-stage clinical study will reduce the company's spending, speed up the potential approval of the drug, and make Acadia a more tempting target for potential acquirers. Beginning on February 10, 2012, Voce Capital sent a letter to the Obagi Board of Directors criticizing the Board's adoption of a poison pill and demanding immediate action to address the company's corporate governance failures. I think that would potentially drive sales of Opdivo. The other candidates in the pipeline include CTX110, CTX120 and CTC130, all for immuno-oncology indications. Always do your own due diligence before buying and selling any stock, and/or consult with a licensed financial adviser. Want to Get Richer? He has over 20 years of stock market experience which include trading, investing, and managing his familys trust as well as his personal account. The company did have its fair share of troubles when the FDA rejected its application for Ocaliva in NASH, and late last year the company withdrew its application filed with the European Medicines Agency for the same. While 2022 started rather quiet as it pertains to M&A, the second quarter was one of the busiest three-month periods for acquisitions in recent years. There's a company called Adicet Bio (ACET 0.46%), ticker there is ACET, I believe. But that deadline has long passed. ET, 5 Reasons to Buy Vertex Pharmaceuticals Now, 3 Biopharma Stocks That Could Help Make You a Fortune. Here's a look at the 10 top takeover targets. RTTNews->. 6 min read Merger and acquisitions (M&A) have been tepid so far in 2020. According to Glenn Hunzinger, U.S. Pharmaceutical & Life Sciences Consulting Solutions Leader at PricewaterhouseCoopers. Sold CoTherix, Inc. to Actelion Pharmaceuticals Ltd.: Mr. Rosen served on the Board of Directors of CoTherix, Inc. Actelion Pharmaceuticals bought out CoTherix for $420M. Type a symbol or company name. The review of the application by the EMA is expected to commence in January 2020 under accelerated assessment. Looking ahead to full-year 2019, the Company expects Jakafi net product revenues to range between $1.65 billion and $1.68 billion, reflecting 20% to 22% growth over the prior year. Other approved drugs in the companys portfolio continue to do well. Aesther Healthcare Acquisition Corp and Ocean Biomedical, Inc. announced that AEHA has filed with the U.S. Securities and Exchange Commission a definitive proxy statement in connection with its proposed business combination with Ocean and with respect to the special meeting of Aesthers stockholders scheduled to be held on February 3, 2023. Its lead product candidate, pimavanserin, designed to treat Parkinson's Disease Psychosis (PDP) has completed a. e have heard similar buzz over the last few months, and as mentioned, the buzz makes sense to us, in no small part because Acadia has had quite an epic stock run over the last year. The rumor involved Pfizer (PFE) being the acquirer. Mergers and acquisition (M&A) activity in India is heating up. Sold Tercica to Ipsen: Mr. King served as President and General Manager of Tercica. The top ten deals in the industry totaled $97 billion in 2020, led by the $39-billion buyout of Alexion Pharmaceuticals ( ALXN) - Get Free Report late in the year by AstraZeneca ( AZN) - Get Free. The report, out from financial news wire Bloomberg, said the California biotech "is exploring a sale and has held preliminary talks with potential buyers, according to people familiar with the matter." These deals haven't come cheap, however. Additionally, Dan is a Scientist and inventor. Gilead Sciences (GILD -1.00%) also has not been shy about making smaller deals. The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc. 2023, Nasdaq, Inc. All Rights Reserved. Brian Orelli: Maybe every biotech in my portfolio, I'd love for each and every one of them to be taken out for a substantial premium. The mergers and acquisitions included in the database are limited by certain criteria, namely that they must be for an entire company not for product licensings, options to acquire or for partial equity stakes. One of the hot topics in the biopharmaceutical world are mergers & acquisitions (M&A). As well Dan has 5 years trading futures, specializing in E-minis and Treasury products. You Might Regret That, History Suggests the S&P 500 Could Soar in 2023. The FDA recently granted Regenerative Medicine Advanced Therapy (RMAT) designation to CTX110, its wholly-owned allogeneic CAR-T cell therapy targeting CD19+ B-cell malignancies. Subscribe to BioPharma Dive. The companys cell therapy candidates include Specific Peptide Enhanced Affinity Receptor (SPEAR) T-cells, which use genetically engineered T-cell receptors, next-generation Tumor Infiltrating Lymphocytes (TiLs) where a patients own T-cells are co-administered with next-generation technology, and HLA-independent TCRs (HiTs) where surface proteins are targeted independently of the peptide-HLA complex. National Institutes of Allergy and Infectious Diseases. The company is also developing CRISPR gene-editing therapeutic candidates for DMD. Learn More. Many times in recent years, premiums on biopharma acquisitions surpassed 100%. That funding can make them less receptive to a buyout and force would-be acquirers to offer more to lock down deals. Whether M&A activity continues will have a significant effect on which startups and drug programs get funded and advanced. Here's the Stock to Buy Now, Join Nearly 1 Million Premium Members And Get More In-Depth Stock Guidance and Research, Motley Fool Issues Rare All In Buy Alert, Copyright, Trademark and Patent Information. The opinions expressed in this article are those of the writer, subject to the InvestorPlace.comPublishing Guidelines. If there's anything we've missed, or any additional information you'd like to see, please reach out and let us know. ALNY also has a deep pipeline with six product candidates in late-stage development. Acquirer Ticker Acquired Ticker Deal value Price/Share Notes Link to the news PR; 01/05/2021: Hologic, Inc. HOLX: Private-German co. $64M-leader in biopsy site markers: https://bwnews.pr/2L3d7lF: Speights: Yeah. Mergers & Acquisitions (M&As) are back in focus in the biotech sector as Merck MRK recently acquired Acceleron Pharma for $180 per share in cash for an approximate total equity value of $11.5 . It is comforting to know that management is out for the shareholder and has a proven record of success. Fun fact: the company was named after Alnilam, the central star of Orions belt and the spelling was slightly modified to make it unique. Zacks Investment Research, Alnylam Pharmaceuticals, Inc. (ALNY) : Free Stock Analysis Report, Biogen Inc. (BIIB) : Free Stock Analysis Report, BioMarin Pharmaceutical Inc. (BMRN) : Free Stock Analysis Report, Adaptimmune Therapeutics PLC (ADAP) : Free Stock Analysis Report, CRISPR Therapeutics AG (CRSP) : Free Stock Analysis Report. Otrexup needs a doctor's prescription and cannot be purchased over the counter. Are you interested in learning more about biotech stocks with exceptional future perspectives and some of the hottest takeover targets of the industry? One of leaders in this field is CRISPR Therapeutics, a Cambridge (MA)-based biopharmaceutical company focused on the discovery and development of transformative genetic medicines for serious human diseases such as hemoglobinopathies, diabetes, or cancer. Disclosure: I am long ATRS, SLTM, ACRX. While oncology and immuno-oncology are the key areas of focus, treatments for rare diseases and gene-editing companies also promise potential, making them lucrative investment areas. According to a Wall Street Journal report, the companies are in talks regarding a possible acquisition deal. Oct 2007 Alphapharma hires Howarth VP of Investor Relations, June 2009 King hires Howarth VP of Investor Relations, Feb 2012 Antares hires Howarth VP of Investor Relations. The Company submitted a Marketing Authorization Application to the. But I think there's also a good fit on Seagen's pipeline too. In early 2017, the rumor mill was spinning with whispers of Gilead (GILD) close to acquiring Incyte. The speculation gained further ground when Denmark-based Novo Nordisk (NYSE:NVO) announced a deal to buy Dicerna, also a RNAi therapeutic company. While there have been a few bolt-in acquisitions here and there, large deals have been rare. A number of clinical trials with Rubraca in various other indications say, prostate, breast, gastroesophageal, pancreatic, and lung cancers are underway or are expected to be initiated in the near-term. Do Not Sell My Personal Information (CA Residents Only). The FDA approval of Voxzogo for achondroplasia, the most common form of dwarfism, has raised BMRNs prospects significantly. Premiums were calculated using the acquired company's share price at the previous trading day's close, Only one therapeutic category is counted for each acquired company. Considering its massive potential, Axsome Therapeutics it is likely to be ranked high on the shopping list of many large pharmaceutical companies for possible acquisition. Clovis Oncology is an American pharmaceutical company specialized in oncology treatments. This cannot be the undisclosed product for which Antares and Pfizer are in a partnership for. ET, Bristol Myers Squibb Wins Another Approval for Its Multimillion-Dollar Cancer Drug, 3 Supercharged Dividend Stocks to Buy If There's a Stock Market Sell-Off, Investors Should Consider This Warren Buffett Advice in 2023, 2 Massive Companies That Have Doubled Their Sales in 5 Years, 2 Stocks to Buy Whether or Not a Recession Is Coming, Warren Buffett Is Raking in $4.84 Billion in Annual Dividend Income From These 6 Stocks, Social Security: 4 Big Changes Washington Wants to Make, Claiming Social Security at 65? Someone is "mistaken" here. Highly anticipated study results are expected in Alzheimers, obesity and Huntingtons, while a pair of high-priced acquisitions could be put to the test. The surge in transactions in the pharmaceutical industry saw 16 deals during 2022 - seemingly the largest number in a decade, worth several billion dollars in value. 10. Clovis Oncology shares have gained 270% since November, and trade around $13. If approved, ValRox will be available for patients well in advance of Pfizer and Sangamo Therapeutics gene therapy Giroctocogene Fitelparvovec, for which the two companies voluntarily paused the phase 3 clinical trial program last year for changes to the protocol. The quest behind the drive is to fill potential gaps in the pipeline. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.*. Big pharma companies will be keen on picking up biotech stocks for deal sizes in the $5 billion to $15 billion range. At the time, I was . According to a report by Implement Consulting Group, a Scandinavian consultancy, "on average only 62% of the M&A deals are successful. Biotech M&A With a Slow Start in 2020: More Deals to Follow? Capsa Healthcare, a leading innovator in healthcare delivery solutions for hospitals, long-term care, and retail pharmacy providers, announced the acquisition of Tryten Technologies Inc., a designer and manufacturer of lightweight, easy to maneuver mobile cart solutions. And trade around $ 13 a significant effect on which startups and drug get. Symbol you want to add appears, add it to My Quotes by selecting it and pressing Enter/Return to... Bmrns prospects significantly newsletter they have run for over a decade, Motley Fool stock,! The $ 5 billion to $ biotech acquisition rumors billion range, 3 Biopharma that..., the companies are in a partnership for more deals to Follow )!, specializing in E-minis and Treasury products CRISPR-focused biotech ovarian cancer not been shy about smaller! 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